Cardiac Center Innovation Awardees

Jennifer Lynch, MD

 
Development and Use of Novel Neuromonitoring Devices During Neonatal Cardiac Surgery
 
Works to improve neuromonitoring during pediatric cardiac surgery
 
Started February 2023 – Received 2nd year funding approval on 2/2/2024

Matt Jolley, MD
Matt Gillespie, MD

 
Optimization of Patient Candidacy and Device Selection for TPVR into Native Outflow Tracts
 
Aims to develop and apply an image-derived, mechanics-based workflow for inserting a TCPV to patient-specific pulmonary artery models
 
Started February 2023 – Received 2nd year funding approval on 2/8/24

Monique Gardner, MD

 
Advanced Cardiac Therapies (ACT) ICU: Biorepository for Heart
 
Performs multi-omic molecular phenotyping on pre- and post-operative bio-samples to gain insight into novel, predictive biomarkers that may reveal mechanistic mediators to target in future interventional trials
 
Started April 2023

Meg Cates, DNP, RN, CCRN

 
Cardiac Center Acute Renal Replacement Therapy (ARRT) Core Team
 
Aims to reduce barriers to initiation and maintenance of ARRT, support clinical decision-making and improve operational infrastructure for timely and consistent ARRT delivery
 
Started February 2023

Laura Mercer-Rosa, MD

 
Implementation of the Cardiac Center Biorepository: Across the Lifespan of Children with Heart Disease
 
Aims to advance translational research, foster successful collaborations, facilitate external funding and support research training for fellows and junior faculty
 
Started April 2023

Emmanuelle Favilla, MD

 
PAC3 Hearts to Home: Discharge Optimization
 
Aims to improve efficiency of patient discharge
 
Started July 2023

David Frank, MD
Jonathan Rome, MD
Katsuhide Maeda, MD, PhD

 
Leveraging an Omics Approach for Discover of Molecular Mechanisms and Therapies for Pulmonary Vein Stenosis (PVS)
 
Aims to better understand PVS by identifying molecular mechanisms orchestrating disease mechanisms early on and provide novel therapies for treatment
 
Started April 2022

Constantine Mavroudis, MD
William Gaynor, MD
Daniel Licht, MD
Todd Kilbaugh, MD

 
Mitochondrial Targeted Diagnostics and Therapeutics in a Swine Model of Cardiac Surgery and Deep Hypothermic Circulatory Arrest
 
Works to determine mitochondrial injury impacting neurological harm and assesses the effect of cyclosporin-A on the reversal of symptoms
 
Started April 2022

Betsy Goldmunts, MD
Mark Fogel, MD
Walter Wichtesey, PhD

 
Machine Learning of Advanced Imaging-Derived Phenotypes (IDPs) and Genomics for Clinical Outcomes Research in Congenital Heart Disease (CHD)
 

Uses machine learning to develop automated techniques for extraction of imaging-derived phenotypes in CHD patients and identify associations between myocardial disease IDPs, genetic variants and outcomes
 
Started April 2022

Matthew Jolley, MD
Lindsay Rogers, MD
Michael Quartermain, MD
David Biko, MD
Kevine Whitehead, MD

 
Quantitative 3D Analysis to Inform Systemic Semilunar Valve (SSV) Repair in Children
 
Creates and applies semi-automatic multimodality 3D-image derived modeling tools for the visualization, quantification and planning of surgical repair in pediatric systemic semilunar valves
 
Just Started

Lyla Hampton, PhD
Alison Burnham, MD
Amanda Shillingford, MD

 
Promoting Engagement, Advocacy, and Access to Developmental Care for Families of Children with Congenital Heart Disease
 
Works to expand the neurodevelopment program, including educational content and family learning programs using technological advances
 
Started March 2002

Ben Kozyak, MD
Katsuhide Maeda, MD, PhD
Jordan Raney, MD

 
Development of a Pulsatile Cavopulmonary Conduit Using Architected Materials and Soft Robotics
 
Aims to improve the Fontan circulation through creation of an electromagnetic robotic system
 
Just Started

Aaron DeWitt, MD
Meryl Cohen, MD
Jessica Eichner, MSN, CRNP-AC
Melissa Greberman, LSW
Jennifer Hwang, MD
Felina Mille, MD
Jennifer Walter, MD, PhD
Jonathan Edelson, MD

 
Improving the Delivery of Serious News to Patients & Families
 
Implements VitalTalk training program for staff
 
In Process

Stephanie Fuller, MD
Lindsay Rogers, MD
Reena Gosh, MD

 
CHOP Cardiac Center Comprehensive Image Library
 
Works to create a web-based platform for sharing images, illustrations and videos
 
Implemented/ongoing

Kevin Whitehead, MD
Reena Gosh, MD
Matthe Jolley, MD
Elizabeth Silvestro, MSE

 
Cardiac Center 3D Imaging Collaborative
 
Aims to support clinical needs through expansion of 3D image modeling
 
In Process

Stacey Drant, MD
Maria Mascarenhas, MD
Jennifer Thorpe, MBA, RD
Michael McBride, PhD
Deborah Lefokowitz, PsyD
Jennifer Sherker, PsyD

Implementation of a Lifestyle Medicine Program into Pediatric Cardiology
 
Focuses on wellness lifestyle training for Cardiac Center patients
 
In Process

Maryam Naim, MD
Paul Stephens, MD
Jessica Eichner, MSN, CRNP
Bridget Clawson, RN

Establishment of a Cardiac Center Bereavement Team
 
Works to establish a program that would provide long-term support for bereaved families and educate providers on how they can help
 
Implemented

Maully Shah, MD
Karen Smoots, MSN, RN
Michael McBride, PhD
Sharna Basu, CRNP
Daniel Freed
Marva Prince
Janis Hardill, CCT, CRAT

21st Century Technology for 21st Century Care
 
Works to implement OME monitoring technology for cardiac electronic implantable devices
 
Implemented

Sherri Kubis, MSN
Amy Romer, MD
Becky Reid, BSN/CNE
Lisa Mitchell, BSN
Katie Montgomery, BSN/CNE
Stacy Peddy, MD
Amy Jo Lisanti, PhD
Kerri Lombardi, APRN, BC, MJ, MBA

Cardiac Center for Resourced Education and Simulation Training (CREST): Innovation Proposal
 
Developed a simulation space for clinical training adjacent to the Cardiac Center IP units
 
Implemented

Tamar Preminger, MD
Therese Giglia, MD
Shobha Natarjan, MD
Kate Fuller, Digital Health Advisor
Rachel Shustak, MD
Alyson Stagg, CRNP
Kylie Geddes, Sr. Improvement Advisor

CHOP Telecardiology Program
 
Provides resources to expand remote home monitoring and telemedicine programs
 
Implemented

Maryam Naim, MD
David Hehir, MD
Benjamin Kozyak, MD
Emily Schwartz, MSN, CRNP
Amanda Seelhorst, BSN

Virtual iPad Parental Presence in Rounds
 
Allows family members who cannot be present at the hospital to participate remotely in patient rounds
 
Implemented

Abby Demianczyk, PhD
Katie Price, CCLS
Melissa Greberman, LSW

Cardiac Connections: Comprehensive Social Support Programming for Cardiac Patients and Families
 
Created social networking activities for Cardiac Center families
 
Not implemented. Funds will go to support other programs/events (for example, Fetal Family Reunion at the Zoo).

Alex Chappel, CCP, LP
Tami Rosenthal, CCP, MBA, FPP
Christy Bosler, PA-C
Lily Tayor, PA-C
Ellen Cannon, PA-C
Jill Bacher, RN
Stephanie Fuller, MD
Ramesh Kovdavatiganti, MD

ScrubIN
 
Improved communication within the clinical perioperative team
 
Utilizing alternative EPIC tools

Natalie Bernard, BSN
Lisa Brogan, BSN
Donna Calfin, BSN
Diana Holbein, CRNP
Austin Turnbull, BSN

Cardiac Center Care Management Program: Addressing the Gap for Complex Patient Care Coordination
 
Created a formal clinical support program for surgical patients transitioning from hospital to home
 
Implemented

David Hehir, MD
Emannuelle Favilla, MD
Kimberly Lin, MD
Alyson Stagg, CRNP
Therese Giglia, MD
Katie Dodds, CRNP
Amanda Shillingford, MD
Victoria Vetter, MD
Bimal Desai, AVP, CHQA
Daria Ferrro, DBHi

A Universal App for Cardiac Center Care Coordination
 
Aims to create an app for clinical follow-up, patient education and communication with clinical staff post-hospitlization
 
In Review Process with IT/EPIC

David Frank, MD

Macromolecular Prodrug Targeting of Pulmonary Vasculopathy in Pulmonary Hypertension
 
Develops new treatments for pulmonary hypertension
 
Ongoing

Matt Jolley, MD

Quantitative 3D Analysis to Inform Tricuspid Valve Repair in HLHS
 
Works to improve surgical and interventional outcomes for valve repair in single ventricle patients through development of new imaging techniques
 
Ongoing

Andy Glatz, MD

The von Willebrand Factor-Angiopoietin Axis and Abnormal Angiogenesis in Single Ventricle Disease: Mechanistic Relationships and Potential Target for Novel Therapy
 
Works to better understand the causes of abnormal blood vessel development in and create novel therapies for congenital heart patients with single ventricle disorders
 
Ongoing